Illuminating luminal B: QSOX1 as a subtype-specific biomarker
نویسندگان
چکیده
منابع مشابه
Luminal B breast cancer subtype displays a dicotomic epigenetic pattern
Luminal B breast tumors have aggressive clinical and biological features, and constitute the most heterogeneous molecular subtype, both clinically and molecularly. Unfortunately, the immunohistochemistry correlate of the luminal B subtype remains still imprecise, and it has now become of paramount importance to define a classification scheme capable of segregating luminal tumors into clinically...
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BACKGROUND Luminal subtype breast cancer accounts for a predominant number of breast cancers. Considering the heterogeneity of the disease, it is urgent to develop novel biomarkers to improve risk stratification and optimize therapy choices. Long non-coding RNA (lncRNA) represents an emerging and understudied class of transcripts that play a significant role in cancer biology. Growing knowledge...
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ژورنال
عنوان ژورنال: Breast Cancer Research
سال: 2013
ISSN: 1465-542X
DOI: 10.1186/bcr3417